MEXICO CITY – A prosecutor who oversaw Mexico's extradition of drug traffickers has resigned – the second senior crime-fighter to quit in a week, an official said Monday.

Jose Luis Santiago Vasconcelos was Mexico's top anti-drug prosecutor for two decades before taking his recent position as deputy attorney general for international affairs.

He resigned for personal reasons, according to an official with the Attorney General's office, who spoke on condition of anonymity because the government has not made an official announcement.

Assistant Attorney General for Organized Crime Noe Ramirez resigned last week as part of a law enforcement shake-up by President Felipe Calderón. His administration has yet to achieve a drop in rampant drug violence despite a massive deployment of soldiers and federal police to fight organized crime.

Calderón has deployed thousands of troops to fight drug cartels who control territory, hold sway over corrupt local police forces and supply most of the cocaine that enters the United States.

Drug gangs have fought back with increasingly bold attacks against police and prosecutors, beheading some and shooting others in front of their homes.

In January, Santiago Vasconcelos said he was targeted for assassination by three men captured in Mexico City with assault rifles and grenade launchers. He said the suspects were going to kill him on Jan. 17 when he was driving home, but were detained that day by Mexico City police.